Nutrition
Establishing Balance in the Gastrointestinal Tract
Paul A. Goldberg, M.P.H., D.C.
[In the second part of this series Dr. Goldberg explores four steps to take
to re-establish balance in the gastrointestinal tract to promote good health
and reverse chronic disease.]
Disruption of the gastrointestinal tract plays a critical role in the creation
of a wide variety of systemic illnesses. Gastrointestinal dysfunction can be
found in many patients who arrive at doctors offices with chronic complaints,
even among those with seemingly unrelated primary complaints such as back pain,
fatigue, headaches, depression, etc.
In chronic health complaints, the amount of abuse inflicted upon the gastrointestinal
tract is often astounding. Years of overeating poor quality foodstuffs far beyond
the patients digestive capacity, too little rest and sleep to allow for
sufficient digestive energy production, ongoing stressors that have upset the
delicate balance of the GI tracts intrinsic nervous system, ingestion
of alcohol, tobacco, coffee, drugs and other toxins which alter the bodys
chemistry, all resulting in a gastrointestinal tract that is severely compromised.
How can the numerous abuses of so many years be addressed? How can the vitality
of the GI tract, essential to the correction of a myriad of chronic health problems,
be achieved?
SPECIFIC MEASURES
Identify and Address Specific Etiological Factors
Each patient is different in regards to the strengths and weaknesses of their
systems and the abuses they have been subjected to. This infinite variety of
patients often requires the counsel of a doctor with good detective skills to
analyze the specific etiological factors involved with each case.i A thorough
case history, physical examination and appropriate laboratory tests should be
performed on each patient to identify these individual traits and then to address
them thoroughly at their roots. There is no pre-packaged program that will fit
the requirements of all patients, and before general measures can be taken (see
below), specifics need to be identified and addressed.
GENERAL MEASURES
I. Allowing for Rest
If there is any single factor almost universally involved in GI disturbances
it is overeating. A sick gastrointestinal tract is an exhausted gastrointestinal
tract. Like any part of the body such as the muscles, an overworked system requires
rest. Continual overeating, use of stimulants such as coffee and the ingestion
of toxic drugs (prescription and non-prescription) deplete the vital energies
of the body. Drugs cannot restore energy to the GI tract. All drugs have toxic
effects and the body must expend energy in trying to neutralize and eliminate
them from the body. This includes materials such as coffee, alcohol, tobacco
and junk food. Like beating a tired horse with a whip, we might get the horse
to move faster for awhile with stimulants of various types, but ultimately the
poor animal breaks down unless given the opportunity to recover its energies.
Unlike the thinking of many, including numerous health care providers, food
does not simply give us energy. Food constitutes raw material the GI tract acts
upon to produce energy. To utilize food, digestion, absorption, assimilation,
cellular excretion and elimination of wastes are called into play, all requiring
the expenditure of significant amounts of energy. To continually eat when the
GI tract is ill is equivalent to requiring a torn muscle to continue to exercise
or to walk upon a broken leg. These are not conditions for healing.
A reduction in food is called for. It may be necessary to limit certain foods
or adopt an appropriate liquid diet with careful supervision. The patient should
conserve energy placed on the digestive system.ii When this is done properly
the improvements are rapid and impressive, assuming that the resting period
is followed by an intelligent, individualized plan of action for the patient
to follow on an ongoing basis.
II. Establishing Healthy Gastrointestinal Micro Flora
The gastrointestinal tract is a delicate environment in which billions of microorganisms
and the influx of ingested materials interact with lifestyle factors in working
for or against establishing a healthy internal environmentiii of the gut. The
intestinal microorganisms are affected by what enters the gut and in turn exert
their influence on the systemic health (or disease) of the individual.
Health promoting intestinal bacteria (known collectively as probiotics) assist
in the processes of digestion and absorption; synthesize nutrients including
B vitamins and vitamin K; influence the production of immune factors such as
secretory IgA; protect us against the presence of disease producing organisms;
are involved with gastric pH;iv promote the health of the intestinal membrane
and also increase our resistance to food poisoning as well as a host of other
functions.
Pathogenic (disease producing) bacteria interfere with digestion and usage of
nutrients, produce toxic waste materials and may cause or contribute to rheumatoid
arthritisv, asthmavi ankylosing spondylitisvii cancerviii, overall immunityix
dermatological problemsx, immunity against viral agentsxi, constipation and
diarrheaxii, ulcerative colitisxiii, Crohns diseasexiv, allergic responsesxv,
and many other health problems.
Gut bacteria are so numerous that the total weight of bacterial cells is estimated
to be three to five pounds, all in fierce competition to establish their presence
in the intestines. Approximately 400 different types of bacteria live in the
small and large intestines although the majority of them are comprised of about
20 species. We ingest and expel bacteria on a daily basis as they are found
in the air we breathe and the food we eat.
In the gut there is an ongoing battle among the different species of bacteria
to obtain dominance. This war serves to keep the disease-producing bacteria
from gaining the upper hand, but only if conditions are appropriate for the
growth of the health-producing bacteria and there are sufficient good bacteria
present.
Clearly, good health depends on a healthy gut and a healthy gut depends on the
presence of adequate amounts of health promoting bacteria to limit the growth
of disease producing (pathogenic) bacteria. Understanding the positive role
of bacteria in the prevention and correction of disease processes will require
a revolutionary change in standard thinking away from the misconception that
all bacteria are simply disease producing agents to be avoided at all costs.
Some specific factors that disturb and limit healthy bacterial growth (and thus
promote the growth of pathogens) include antibiotics, antacids, laxatives, long-term
stress, simple carbohydrates, steroids and non-steroidal anti-inflammatory drugs
(NSAIDS).
Improving the gut flora requires allowing adequate gut rest, and nourishing
the body properly. An additional step is to bolster the amounts of health promoting
bacteria through the use of appropriate probiotic supplements. These are best
taken in the same form as our ancestors did for millions of years.
Since man first
appeared on the planet until very recently, human beings acquired a wide variety
of probiotic bacteria from the foods they ate that were contained in the soil.
These are now referred to as Homeostatic Soil Organisms (HSOs). HSOs are bacteria
that live in the soil and make the soil more fertile. They release an assortment
of enzymes that kill off yeasts, molds and other materials that hinder plants
from growing. Ingested by humans, as they were in the past, they are valuable
allies in combating disease producing bacteria, viruses, yeasts, molds and fungi.
In regulating the microorganisms of the gastrointestinal tract they help to
maintain a state of homeostasis in the GI tract and thereby in the body as a
whole.
Our ancestors ingested significant amounts of Homeostatic Soil Organisms on
a daily basis. With every root and vegetable they pulled from the soil and with
every fruit they picked up from the ground in their gathering activities came
millions of microorganisms. Our hunting and gathering ancestors of hundreds
of thousands of years ago, as well as our farming ancestors of just a hundred
years ago, were not so fastidious to wash and scrub off every speck of dirt.
The carrot pulled out of the ground was simply brushed off and eaten, dirt and
all. Meat and root vegetables were often buried in the ground to preserve them
and then dug back up and ingested. Our pet dogs engage in the same type of behavior
in burying their bones. It is notable that despite the far greater exposure
and ingestion of bacteria that our pet canines engage in, that they generally
have far less illness than we do, unless we keep them inside and limit their
opportunity to dig around in the soil. Current agricultural practices such as
germicides, radiation and fungicides meant to kill harmful bacteria and other
microorganisms kill off healthful HSOs leaving our foodstuffs virtually sterile
in comparison with the dietaries of our ancestors.
Most probiotic supplements on the market have to contain billions of organisms
in the hope that a few might survive the stomach acids and digestive juices
to reach the small and large intestines. HSOs are highly viable organisms, however,
and are able to survive the stomach acid on their journey to the intestines.
Since humans have been ingesting HSOs for millions of years, the body seems
to recognize them like foodstuffs and accordingly, does not attack them. Once
implanted, HSOs compete with pathogens in the gut and work to displace them.
They tend to be aggressive against molds, yeast, pathogenic bacteria and perhaps
even some viruses.
HSOs are hardly new on the scene or a recent invention. Their usage is simply
going back to a common behavior of our ancestors. A significant advantage in
taking HSOs in supplemental form is that we avoid parasites and other harmful
materials that can be found in the dirt in your backyard while still receiving
the benefits of the HSOs themselves.
The use of HSOs fits in logically with the Hygiene Hypothesis discussed
in part one of this article. In public health we are becoming increasingly aware
that the bulk of scientific/epidemiological studies supports the idea that exposure
to a wide variety of bacteria may help prevent numerous disorders including
asthma, allergies, autoimmune disorders and others.xvi Supplemental HSOs can
help in this regard in both the prevention of chronic disease states and in
their reversal. A number of studies are already underway to investigate this.
Common sense and clinical experience has already made evident to many practitioners
the wisdom in providing HSOs to their patients and to themselves.xvii
A pilot study directed by the author at the Goldberg Clinic involved 16 subjects
between the ages of 20 to 65, with a variety of chronic digestive and immune
disorders. The subjects were placed on a protocol of HSOs for 120 days. Subjects
were selected based on the types of difficulties they were having and on the
highly resistant nature of their problems to both medical treatments and alternative/complementary
care. All had been ill for a minimum of three years, with several having complex
health problems dating back 10 years and longer.
Subjects were evaluated by changes measured via laboratory analysis and by subjective
feedback from the subjects regarding changes in their conditions.
Fifteen of the 16 subjects reported clinical improvement with relief of symptoms
and positive changes in their overall well-being. Eight of nine subjects had
a reduction in Candida (yeast) growth verified by stool and/or blood titers.
Three subjects who had suffered from long-term chronic constipation with laxative
dependency were able to move their bowels daily without the use of laxatives.
Four patients who had been diagnosed with chronic fatigue syndrome
reported freedom from their symptoms at the end of the 120-day period and an
additional three subjects with chronic irritable bowel syndrome
reported between 25 to 100 percent improvement. A radiologist with chronic pulmonary
fungal infection of several years duration reported a dramatic improvement in
her ability to breathe along with significant improvement in her spirometer
readings as evaluated by her medical pulmonologist. Particularly notable to
the author were the improvements seen in three subjects with chronic asthma
whom were able to reduce their inhalant medications by 50 percent or more over
the 120 day study period. Details of the study will be published in a supplement
to Vol. 4 of the medical journal Progress in Nutrition.
III. Establishment of Appropriate Behaviors to Prevent Re-occurrences of
Health Problems
The patient should make a variety of lifestyle improvements under the doctors
supervision. Resting their gastrointestinal tract, avoiding toxins, incorporating
proper dietary measures and improving the bacterial flora by ingesting HSOs,
can all be undone if there is a return to the patients previous habits
that ultimately contributed to their illness. Many individuals still believe
in cures in the sense that once well, they believe they can return
to the prior habits that made them ill initially. Often the patient has a false
sense of security once they are feeling better. They gradually start to fall
back into their old, comforting, unhealthy habits once again. Just one
cup of coffee, just an occasional cigarette, just one big pepperoni pizza, overindulgence
in simple carbohydrates cant hurt on special occasions, and so what if
I stay up late all this week, I will make up for it over the weekend by sleeping
late on Sunday.
At first the patient notices little difference, for the body has been able to
set aside some reserves to cope with a limited amount of abuse. The abuses,
however, tend to become more and more common. A week, a month, or a year later,
however, the patient awakes to the unhappy fact that their prior gastrointestinal,
arthritic, fatigue, dermatological or other problem(s) have returned. The glorious
vitality begins to fade. Unfortunately the response of the patient may then
become, I guess the steps I took with the doctor didnt really fix
my problem, so off they go in search of a cure or simply give
up and sink further and further into illness.
The gastrointestinal tract, like the other body systems, can only take so much
abuse for so long before pathologies are created that may not always be easily
reversed. It is therefore important to stress to the patient that a return to
old unhealthy ways will cause a return of their symptoms and the longer they
persist in such behaviors the more difficult reversing the problems becomes.
Gastrointestinal functioning, with its many positive influences on overall health
and healthy enjoyment of lifes many beautiful offerings, is too precious
to squander.
Summary
Gastrointestinal problems are responsible for many of the systemic chronic illnesses
people suffer from in the United States. Each person is different and most will
initially require an individualized program of care under the supervision of
an experienced practitioner to identify their problems and assist them in their
quest for good health. In addition to the identification of specific etiological
factors, there are three basics applicable in almost every case:
References & Endnotes
i For further discussion see Infinite Variety An Introduction To Biochemical
Individuality by P.A. Goldberg in Todays Chiropractic January/February
2000, May/June 2000, and September/October 2000.
ii Fasting is not necessary for all patients and should never be forced upon
anyone uncomfortable with it. The majority of our clients have done excellently
with a liquid diet or restricted dietary for a period. Both can usually be performed
on an outpatient basis greatly reducing cost and inconvenience to the patient.
iii French Physiologist Claude Bernard (1813-1878) coined the term milieu
interieur)
iv Health promoting bacteria (probiotics) generally acidify the colon, limiting
the growth of many pathogenic bacteria.
v Ebringer, A. Cox, N.L. Abulijadayel, I., et. al.Klebsiella antibodies in ankylosing
spondylitis and Proteus antibodies in rheumatoid arthritis. Brit.J. Rheum 1988,27
vi J Immunol 1998 March 15; 160 (6): 2555-9
vii Antibody Responses to Gut Bacteria in Ankylosing Spondylitis, Rheumatoid
Arthritis, Crohns disease and Ulcerative Colitis: H. Tiwana, et. al. Published
in Rheumatology International SpringerVerlad. Article accepted 18 December,
1996
viii Textbook of Gastroenterology Volume Two second edition Tadataka Yamada
et. al., pages 1917-1918
ix Tilg H ( 1997) New insights into the mechanisms of interferon alfa:
An immunoregulatory andanti-inflammatory cytokine. Gastroenterology 112:
101701021.
x Clin. Exp. Allergy 2000, 30 1230-1234 Exposure to endotoxin or other
bacterial components might protect against the development of atopy
xi Weekes, D (1993), Management of herpes simplex and virostatic bacterial
agent, E.E.N.T. Diges. 25
xii See any standard text in Gastroenterology for these relationships
xiii Ibid
xiv Omahony, S., Anderson, N, et. al. Systemic and mucosal antibodies
to Klebsiella in patients with Crohns disease, Ann. Rheum Dis 1992,
51, 1296-1300
xv F.D. Martinez, PG Holt: Role of Microbial Burden in Aetiology of Allergy
and Asthma. Lancet 1999, 354 (suppl 2).
xvi Voelker, Rebecca The Hygiene Hypothesis JAMA March 8, 2000 Vol
283 No.10
xvii Martinez, Fernando; The Coming of Age of The Hygiene Hypothesis
Respir Res 2001 2: 129-132
xviii For those raising all their own foods in good soil and living a life in
close contact with the natural world, there would be less need to utilize HSO
supplementation.
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